72963-27-0

72963-27-0 structure
72963-27-0 structure
  • Name: L-Tyrosine-d2
  • Chemical Name: (2S)-2-amino-3,3-dideuterio-3-(4-hydroxyphenyl)propanoic acid
  • CAS Number: 72963-27-0
  • Molecular Formula: C9H9D2NO3
  • Molecular Weight: 183.20100
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-06-09 17:27:09
  • Modify Date: 2024-01-08 21:18:16
  • L-Tyrosine-d2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

Name (2S)-2-amino-3,3-dideuterio-3-(4-hydroxyphenyl)propanoic acid
Synonyms L-4-Hydroxyphenyl(alanine-3,3-d2)
MFCD00144690
L-Tyrosine-3,3-d2
Description L-Tyrosine-d2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Melting Point >300ºC (dec.)(lit.)
Molecular Formula C9H9D2NO3
Molecular Weight 183.20100
Exact Mass 183.08600
PSA 83.55000
LogP 1.04690
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport