L-Tyrosine-d2

Modify Date: 2024-01-08 21:18:16

L-Tyrosine-d2 Structure
L-Tyrosine-d2 structure
Common Name L-Tyrosine-d2
CAS Number 72963-27-0 Molecular Weight 183.20100
Density N/A Boiling Point N/A
Molecular Formula C9H9D2NO3 Melting Point >300ºC (dec.)(lit.)
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of L-Tyrosine-d2


L-Tyrosine-d2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

 Names

Name (2S)-2-amino-3,3-dideuterio-3-(4-hydroxyphenyl)propanoic acid
Synonym More Synonyms

 L-Tyrosine-d2 Biological Activity

Description L-Tyrosine-d2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Melting Point >300ºC (dec.)(lit.)
Molecular Formula C9H9D2NO3
Molecular Weight 183.20100
Exact Mass 183.08600
PSA 83.55000
LogP 1.04690

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Synonyms

L-4-Hydroxyphenyl(alanine-3,3-d2)
MFCD00144690
L-Tyrosine-3,3-d2
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