15302-10-0

15302-10-0 structure

Name: Clibucaine
Chemical Name: N-(2,4-dichlorophenyl)-3-piperidin-1-ylbutanamide
CAS Number: 15302-10-0
Molecular Formula: C₁₅H₂₀Cl₂N₂O
Molecular Weight: 315.24
Catalog: Research Areas Others
Create Date: 2018-03-06 08:00:00
Modify Date: 2024-01-23 19:11:49
Clibucaine is a piperidine derivative possessing local anesthetic properties. Clibucaine can be used as a local anesthetic agent[1].

Name	N-(2,4-dichlorophenyl)-3-piperidin-1-ylbutanamide
Synonyms	Clibucaina 3-Piperidino-buttersaeure-(2,4-dichlor-anilid) Clibucaine Clibucaina [INN-Spanish] 3-piperidino-butyric acid-(2,4-dichloro-anilide) Clibucainum [INN-Latin]

Description	Clibucaine is a piperidine derivative possessing local anesthetic properties. Clibucaine can be used as a local anesthetic agent[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Dennie Van Den Heuvel, et al. Gastro-retentive oral dosage unit containing a local anaesthetic. Patent, WO2023094100A1.

Density	1.255g/cm3
Boiling Point	466.8ºC at 760mmHg
Molecular Formula	C₁₅H₂₀Cl₂N₂O
Molecular Weight	315.24
Flash Point	236.1ºC
Exact Mass	314.09500
PSA	35.83000
LogP	4.78380
Vapour Pressure	6.86E-09mmHg at 25°C
Index of Refraction	1.585

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN3712310

CHEMICAL NAME :: 1-Piperidinepropionanilide, 2',4'-dichloro-beta-methyl-

CAS REGISTRY NUMBER :: 15302-10-0

BEILSTEIN REFERENCE NO. :: 0249881

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C15-H20-Cl2-N2-O

MOLECULAR WEIGHT :: 315.27

WISWESSER LINE NOTATION :: T6NTJ AY1&1VMR BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 220 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955

HS Code	2933399090

554-00-7

15302-10-0

Literature: Wilder Smith; Hofstetter Helvetica Chimica Acta, 1955 , vol. 38, p. 1085,1089,1091

110-89-4

99057-78-0

15302-10-0

Literature: Wilder Smith; Hofstetter Helvetica Chimica Acta, 1955 , vol. 38, p. 1085,1089,1091

110-89-4

15302-10-0

Literature: Wilder Smith; Hofstetter Helvetica Chimica Acta, 1955 , vol. 38, p. 1085,1089,1091

Precursor 2
110-89-4 554-00-7
DownStream 0

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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