548-08-3
548-08-3 structure
- Name: Roemerine
- Chemical Name: (–)-roemerine
- CAS Number: 548-08-3
- Molecular Formula: C18H17NO2
- Molecular Weight: 279.33300
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridazine
- Create Date: 2018-02-27 08:00:00
- Modify Date: 2026-06-30 13:15:13
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Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1].
| Name | (–)-roemerine |
|---|---|
| Synonyms |
5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-7-methyl-, (7)
(-)-Roemerine (R)-(-)-roemerine Remerine Remerin (-)-Roemine (-)-Aporheine (-)-Roemarine (-)-N-Methylanonaine [7,(-)]-6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline (-)-romerine (6aR)-roemerine (6-6-Methyl-1,2-(methylenedioxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline roemerine (-)-Remerine |
| Description | Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.269±0.06 g/cm3 (20 ºC 760 Torr) |
|---|---|
| Melting Point | 102-103 ºC |
| Molecular Formula | C18H17NO2 |
| Molecular Weight | 279.33300 |
| Exact Mass | 279.12600 |
| PSA | 21.70000 |
| LogP | 3.10530 |
| Hazard Codes | Xi |
|---|
| Precursor 0 | |
|---|---|
| DownStream 1 | |
