Roemerine

Modify Date: 2025-08-26 17:28:42

Roemerine structure	Common Name	Roemerine
	CAS Number	548-08-3	Molecular Weight	279.33300
	Density	1.269±0.06 g/cm3 (20 ºC 760 Torr)	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇NO₂	Melting Point	102-103 ºC
	MSDS	N/A	Flash Point	N/A

Use of Roemerine

Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1].

Name	(–)-roemerine
Synonym	More Synonyms

Description	Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
References	[1]. M You, et al. (-)-Roemerine, an Aporphine Alkaloid From Annona Senegalensis That Reverses the Multidrug-Resistance Phenotype With Cultured Cells. J Nat Prod. 1995 Apr;58(4):598-604.

Density	1.269±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	102-103 ºC
Molecular Formula	C₁₈H₁₇NO₂
Molecular Weight	279.33300
Exact Mass	279.12600
PSA	21.70000
LogP	3.10530
InChIKey	JCTYWRARKVGOBK-CQSZACIVSA-N
SMILES	CN1CCc2cc3c(c4c2C1Cc1ccccc1-4)OCO3

Hazard Codes	Xi

Precursor 0
DownStream 1
CAS#:36285-03-7 Dehydroroemerine

Name: Selectivity ratio of Kb for human adrenergic alpha1A receptor to Kb for human 5-HT2A ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4258734

Name: Displacement of ATP-dependent [3H]vinblastine from P-glycoprotein in human multidrug-...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1024958

Name: Selectivity ratio of Kb for human adrenergic alpha1D receptor to Kb for human adrener...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4258733

Name: Selectivity ratio of Kb for human adrenergic alpha1D receptor to Kb for human 5-HT2A ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4258736

Name: Cytotoxicity against human ZR-75-1 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: ZR-75-1
External Id: CHEMBL1024956

Name: Selectivity ratio of Kb for human adrenergic alpha1B receptor to Kb for human 5-HT2A ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4258735

Name: Cytotoxicity against human multidrug resistant KBV1 cells in absence of vinblastine a...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1024957

Name: Antagonist activity at human adrenergic alpha1D receptor expressed in HEK293 cells as...
Source: ChEMBL
Target: Alpha-1D adrenergic receptor
External Id: CHEMBL4258730

Name: Cytotoxicity against mouse P388 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: P388
External Id: CHEMBL1024954

Name: Antagonist activity at human adrenergic alpha1B receptor expressed in HEK293 cells as...
Source: ChEMBL
Target: Alpha-1B adrenergic receptor
External Id: CHEMBL4258729

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(6aR)-roemerine

(R)-(-)-roemerine

(-)-romerine

Roemerine

(-)-Aporheine

(-)-Remerine

(-)-Roemarine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Roemerine
Price: Check
Purity: 98.0%
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BioBioPha
China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: roemerine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

naturewill
China
Product Name: Roemerine
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.