Roemerine
Roemerine structure
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Common Name | Roemerine | ||
|---|---|---|---|---|
| CAS Number | 548-08-3 | Molecular Weight | 279.33300 | |
| Density | 1.269±0.06 g/cm3 (20 ºC 760 Torr) | Boiling Point | N/A | |
| Molecular Formula | C18H17NO2 | Melting Point | 102-103 ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of RoemerineRoemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1]. |
Summary: (–)-Roemerine, also known as roemerine, has a CAS number of 548-08-3 and a molecular formula of C18H17NO2 with a molecular weight of 279.33300. Roemerine, an aporphine alkaloid isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein, reversing the multidrug-resistance phenotype. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (–)-roemerine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.269±0.06 g/cm3 (20 ºC 760 Torr) |
|---|---|
| Melting Point | 102-103 ºC |
| Molecular Formula | C18H17NO2 |
| Molecular Weight | 279.33300 |
| Exact Mass | 279.12600 |
| PSA | 21.70000 |
| LogP | 3.10530 |
| InChIKey | JCTYWRARKVGOBK-CQSZACIVSA-N |
| SMILES | CN1CCc2cc3c(c4c2C1Cc1ccccc1-4)OCO3 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
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This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 0 | |
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| DownStream 1 | |
CAS#:36285-03-7This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (6aR)-roemerine |
| (R)-(-)-roemerine |
| (-)-romerine |
| Roemerine |
| (-)-Aporheine |
| (-)-Remerine |
| (-)-Roemarine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of (–)-roemerine? |
| A: CAS number of (–)-roemerine is 548-08-3. |
| Q: What is the English name of (–)-roemerine? |
| A: The English name of (–)-roemerine is (–)-roemerine. |
| Q: What is the SMILES notation of (–)-roemerine? |
| A: SMILES notation of (–)-roemerine is CN1CCc2cc3c(c4c2C1Cc1ccccc1-4)OCO3. |
| Q: What is the InChIKey of (–)-roemerine? |
| A: InChIKey of (–)-roemerine is JCTYWRARKVGOBK-CQSZACIVSA-N. |
| Q: What is the molecular formula of (–)-roemerine? |
| A: Molecular formula of (–)-roemerine is C18H17NO2. |
| Q: What is the melting point of (–)-roemerine? |
| A: Melting point of (–)-roemerine is 102-103 ºC. |
| Q: What are the downstream products of (–)-roemerine? |
| A: Related downstream products(CAS) of (–)-roemerine: 36285-03-7. |
| Q: What is the polar surface area (PSA) of (–)-roemerine? |
| A: Polar surface area (PSA) of (–)-roemerine is 21.70000. |
| Q: What are the uses of (–)-roemerine? |
| A: Main uses of (–)-roemerine: Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1]. |
| Q: What is the molecular weight of (–)-roemerine? |
| A: Molecular weight of (–)-roemerine is 279.33300. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |