149732-52-5

149732-52-5 structure

Name: 1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
Chemical Name: 1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
CAS Number: 149732-52-5
Molecular Formula: C₁₉H₁₆O₃
Molecular Weight: 292.33
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2017-11-28 22:28:41
Modify Date: 2024-04-09 11:05:37
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively[1].

Name	1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Description	1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
References	[1]. Yang Liu, et al. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2(3):270-280.