1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Modify Date: 2024-04-09 11:05:37

1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one Structure
1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one structure
Common Name 1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
CAS Number 149732-52-5 Molecular Weight 292.33
Density N/A Boiling Point N/A
Molecular Formula C19H16O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one


1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively[1].

 Names

Name 1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

  Biological Activity

Description 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively[1].
Related Catalog
References

[1]. Yang Liu, et al. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2(3):270-280.

 Chemical & Physical Properties

Molecular Formula C19H16O3
Molecular Weight 292.33
Exact Mass 292.11000
PSA 57.53000
LogP 3.94970