94825-44-2

94825-44-2 structure

Name: Guanosine 5′-[γ-thio]triphosphate
Chemical Name: tetralithium,[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
CAS Number: 94825-44-2
Molecular Formula: C₁₀H₁₂Li₄N₅O₁₃P₃S
Molecular Weight: 562.97800
Catalog: Research Areas Others
Create Date: 2018-12-01 13:34:26
Modify Date: 2025-08-25 09:20:51
GTPγS (tetralithium) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS (tetralithium) to couple with G- protein α, to study its effect on kinase activity. GTPγS (tetralithium) acts as a component of lysis buffer[1][2][3][4].

Name	tetralithium,[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
Synonyms	EINECS 305-606-1 GTP\|AS tetralithium salt MFCD00135151 GTP-\|A-S-Li4 Guanosine5'-(Trihydrogen Diphosphate) P'-Anhydride With Phosphorothioic Acid Lithiumsalt (1:4) Guanosine 5′-[γ-thio]triphosphate Gtp-Gamma-S Tetralithium Salt

Description	GTPγS (tetralithium) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS (tetralithium) to couple with G- protein α, to study its effect on kinase activity. GTPγS (tetralithium) acts as a component of lysis buffer[1][2][3][4].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Julie G Hensler, et al. Differential Regulation of 5-HT1A Receptor-G Protein Interactions in Brain Following Chronic Antidepressant Administration. Neuropsychopharmacology. 2002 May;26(5):565-73. [2]. Li-Bin Liu, et al. Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes. J Biol Chem. 2003 Aug 8;278(32):30157-69. doi: 10.1074/jbc.M301511200. [3]. Xufeng Wu, et al. Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell. 2002 May;13(5):1735-49. [4]. Pilar Sánchez-Blázquez, et al. Brain-specific Galphaz interacts with Src tyrosine kinase to regulate Mu-opioid receptor-NMDAR signaling pathway. Cell Signal. 2009 Sep;21(9):1444-54.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport