Guanosine 5′-[γ-thio]triphosphate structure
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Common Name | Guanosine 5′-[γ-thio]triphosphate | ||
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CAS Number | 94825-44-2 | Molecular Weight | 562.97800 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C10H12Li4N5O13P3S | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Guanosine 5′-[γ-thio]triphosphateGTPγS (tetralithium) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS (tetralithium) to couple with G- protein α, to study its effect on kinase activity. GTPγS (tetralithium) acts as a component of lysis buffer[1][2][3][4]. |
Name | tetralithium,[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate |
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Synonym | More Synonyms |
Description | GTPγS (tetralithium) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS (tetralithium) to couple with G- protein α, to study its effect on kinase activity. GTPγS (tetralithium) acts as a component of lysis buffer[1][2][3][4]. |
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Related Catalog | |
References |
Molecular Formula | C10H12Li4N5O13P3S |
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Molecular Weight | 562.97800 |
Exact Mass | 563.00100 |
PSA | 354.87000 |
LogP | 0.76530 |
Storage condition | 20°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | 26-36 |
RIDADR | NONH for all modes of transport |
Brain-specific Galphaz interacts with Src tyrosine kinase to regulate Mu-opioid receptor-NMDAR signaling pathway.
Cell Physiol. Biochem. 21 , 1444-54, (2009) There is a certain cross-talk in the nervous system between N-methyl-D-aspartate receptors (NMDARs) and Mu-opioid receptors (MORs). While NMDARs participate in the desensitization of MORs, these in tu... |
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High-level production and characterization of a G-protein coupled receptor signaling complex.
FASEB J. 276 , 4515-28, (2009) Elucidation of the molecular details of signal transduction through G-protein coupled receptors (GPCRs) awaits the solution of high-resolution structures of the receptor species involved in passing th... |
EINECS 305-606-1 |
GTP|AS tetralithium salt |
MFCD00135151 |
GTP-|A-S-Li4 |
Guanosine5'-(Trihydrogen Diphosphate) P'-Anhydride With Phosphorothioic Acid Lithiumsalt (1:4) |
Guanosine 5′-[γ-thio]triphosphate |
Gtp-Gamma-S Tetralithium Salt |