| Name | dabsyl chloride |
|---|---|
| Synonyms |
EINECS 260-235-1
4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonyl chloride MFCD00007444 |
| Description | Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. |
|---|---|
| Related Catalog | |
| In Vitro | Dabsyl chloride can give rise to mono-Dabsyl and bis-Dabsyl derivatives in the presence of multiple amino groups. Furthermore with respect to OPA derivatization, Dabsyl chloride can react with primary and also with secondary amines[1]. |
| Cell Assay | Selected mouse brain samples from either cortical or striatal regions (100 mg wet weight) and neuroblastoma cells (SH-SY5Y) pellet derived from 25 cm2 flask are treated with 500 μL of 0.1 M HCl containing 0.2% TDGA, sonicated for 10 min (only for brain tissue), and then centrifuged at 14000 g for 30 min. The supernatant is freeze-dried. 50 μL of reaction buffer and 100 μL of 15 mM Dabsyl chloride are added to the tube and derivatized. |
| References |
| Density | 1.29 g/cm3 |
|---|---|
| Boiling Point | 483.6ºC at 760 mmHg |
| Melting Point | 185 °C (dec.)(lit.) |
| Molecular Formula | C14H14ClN3O2S |
| Molecular Weight | 323.79800 |
| Flash Point | 246.3ºC |
| Exact Mass | 323.05000 |
| PSA | 70.48000 |
| LogP | 5.17630 |
| Index of Refraction | 1.607 |
| Storage condition | −20°C |
| Water Solubility | DMF: soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
|
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C |
| Risk Phrases | R22;R34 |
| Safety Phrases | S26-S36/37/39-S45-S27 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| RTECS | DB8927800 |
| Packaging Group | II |
| Hazard Class | 8 |
| HS Code | 2927000090 |
| HS Code | 2927000090 |
|---|---|
| Summary | 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |