874-14-6

874-14-6 structure

Name: 1,3-Dimethyluracil
Chemical Name: 1,3-Dimethyluracil
CAS Number: 874-14-6
Molecular Formula: C₆H₈N₂O₂
Molecular Weight: 140.140
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Urinary (urea)pyrimidine
Create Date: 2018-08-02 08:33:23
Modify Date: 2024-01-02 11:53:21
1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively[1][2].

Name	1,3-Dimethyluracil
Synonyms	N1,N3-Dimethyluracil 1,3-dimethylpyrimidine-2,4-dione 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl- 1,3-Dimethyl-2,4(1H,3H)-pyrimidinedione MFCD00038065 1,3-dimethyluracil Uracil, 1,3-dimethyl- 1,3-dimethylpyrimidine-2,4(1H,3H)-dione EINECS 212-856-4

Description	1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Stoessel D, et al. Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease. Front Aging Neurosci. 2018 Mar 5;10:51. [2]. Güney M, et al. Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3261-3.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36
Safety Phrases	S22-S24/25-S39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2933599090

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%