117704-65-1

117704-65-1 structure

Name: Pradimicin A
Chemical Name: pradimicin A
CAS Number: 117704-65-1
Molecular Formula: C₄₀H₄₄N₂O₁₈
Molecular Weight: 840.78
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2016-10-31 03:22:04
Modify Date: 2024-01-02 15:01:17
Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].

Name	pradimicin A

Description	Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> SARS-CoV
Target	MIC: 4 μg/mL (Candida rugosa)[1]
References	[1]. Miyanishi W, et al. d-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A. Bioorg Med Chem. 2021 Dec 27;55:116590. [2]. Nakagawa Y, Doi T, Masuda Y, Takegoshi K, Igarashi Y, Ito Y. Mapping of the primary mannose binding site of pradimicin A. J Am Chem Soc. 2011 Nov 2;133(43):17485-93.

Precursor 0
DownStream 3
91-09-8 150134-46-6 117704-66-2