Pradimicin A

Modify Date: 2025-08-27 16:57:01

Pradimicin A structure	Common Name	Pradimicin A
	CAS Number	117704-65-1	Molecular Weight	840.78
	Density	1.688g/cm3	Boiling Point	1120.269°C at 760 mmHg
	Molecular Formula	C₄₀H₄₄N₂O₁₈	Melting Point	N/A
	MSDS	N/A	Flash Point	631.316°C

Use of Pradimicin A

Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].

Name	pradimicin A

Description	Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> SARS-CoV
Target	MIC: 4 μg/mL (Candida rugosa)[1]
References	[1]. Miyanishi W, et al. d-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A. Bioorg Med Chem. 2021 Dec 27;55:116590. [2]. Nakagawa Y, Doi T, Masuda Y, Takegoshi K, Igarashi Y, Ito Y. Mapping of the primary mannose binding site of pradimicin A. J Am Chem Soc. 2011 Nov 2;133(43):17485-93.

Density	1.688g/cm3
Boiling Point	1120.269°C at 760 mmHg
Molecular Formula	C₄₀H₄₄N₂O₁₈
Molecular Weight	840.78
Flash Point	631.316°C
Exact Mass	840.25900
PSA	320.56000
LogP	0.17010