33755-53-2
33755-53-2 structure
- Name: (+)-Biotin-ONP
- Chemical Name: (4-nitrophenyl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
- CAS Number: 33755-53-2
- Molecular Formula: C16H19N3O5S
- Molecular Weight: 365.404
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-17 19:12:41
- Modify Date: 2026-07-01 07:56:37
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(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | (4-nitrophenyl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate |
|---|---|
| Synonyms |
Biotin π-nitrophenyl ester
BNP d-Biotin p-nitrophenyl ester Biotinp-nitrophenyl ester (HPLC) D-(+)-biotin 2-nitrophenyl ester 4-Nitrophenyl (+)-biotinate, d-Biotin p-nitrophenyl ester, BNP 4-Nitrophenyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate BNP,D-Biotin 4-nitrophenyl ester 1,1'-Binaphthyl-2,2'-diyl phosphate 4-Hydroxy-3,5-dioxa-4-phospha(V)-3H-cyclohta[2,1-a:3,4-a']dinaphthalene-4-one (+)-Biotin 4-Nitrophenyl Ester 4-Nitrophenyl 5-((3aS,4S,6-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate D-(+)-Biotin 4-nitrophenyl ester Biotin-p-nitrophenyl ester biotinyl-4-nitrophenyl ester 5-[(3,6S,6aS)-2-keto-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]valeric acid (4-nitrophenyl) ester (+)-Biotin 4-nitrophenyl ester Biotinyl-4-nitrophenyl ester D-BIOTIN P-NITROPHENYL ESTER 4-Hydroxy-4-oxodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphin Monoclonal Anti-NPPB antibody produced in mouse Brain Natriuretic Ptide EIA Kit (4-nitrophenyl) 5-[(3,6S,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]pentanoate Human B-type Natriuretic Protein 4-Nitrophenyl (+)-biotinate D-biotin 4-nitrophenyl ester 4-NITROPHENYL (+)-BIOTINATE Biotin-ONp Novabiochem D-Biotin P-Nitrophenyl Ester BIOTIN-ONP D-Biotin p-nitrophenyl ester MFCD00005540 (+)-Biotin4-NitrophenylEster> 4-Hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphin-4-one BIOTIN-ONP BIOTIN P-NITROPHENYL ESTER BNP, D-Biotin 4-nitrophenyl ester Phosphoric acid 1,1'-binaphthalene-2,2'-diyl ester |
| Description | (+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 642.9±50.0 °C at 760 mmHg |
| Melting Point | 163-165ºC |
| Molecular Formula | C16H19N3O5S |
| Molecular Weight | 365.404 |
| Flash Point | 342.6±30.1 °C |
| Exact Mass | 365.104553 |
| PSA | 138.55000 |
| LogP | 1.89 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.584 |
| Safety Phrases | S22-S24/25 |
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33755-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239 |
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33755-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239 |
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33755-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239 |
