(+)-Biotin-ONP structure
|
Common Name | (+)-Biotin-ONP | ||
|---|---|---|---|---|
| CAS Number | 33755-53-2 | Molecular Weight | 365.404 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 642.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H19N3O5S | Melting Point | 163-165ºC | |
| MSDS | N/A | Flash Point | 342.6±30.1 °C | |
Use of (+)-Biotin-ONP(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | (4-nitrophenyl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate |
|---|---|
| Synonym | More Synonyms |
| Description | (+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 642.9±50.0 °C at 760 mmHg |
| Melting Point | 163-165ºC |
| Molecular Formula | C16H19N3O5S |
| Molecular Weight | 365.404 |
| Flash Point | 342.6±30.1 °C |
| Exact Mass | 365.104553 |
| PSA | 138.55000 |
| LogP | 1.89 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.584 |
| Safety Phrases | S22-S24/25 |
|---|
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(+)-Biotin-ONP CAS#:33755-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239 |
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(+)-Biotin-ONP CAS#:33755-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239 |
|
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(+)-Biotin-ONP CAS#:33755-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239 |
| 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, 4-nitrophenyl ester, (3aS,4S,6aR)- |
| Biotin-p-nitrophenyl ester |
| D-biotin 4-nitrophenyl ester |
| MFCD00005540 |
| D-Biotin P-Nitrophenyl Ester |
| (+)-Biotin 4-nitrophenyl ester |
| Biotinyl-4-nitrophenyl ester |
| D-(+)-biotin 2-nitrophenyl ester |
| 4-Nitrophenyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate |
| BNP,D-Biotin 4-nitrophenyl ester |
| 4-Nitrophenyl (+)-biotinate |