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3868-36-8

3868-36-8 structure
3868-36-8 structure
  • Name: 8-(Phenylmethoxy)guanosine
  • Chemical Name: 8-Benzyloxyguanosine
  • CAS Number: 3868-36-8
  • Molecular Formula: C17H19N5O6
  • Molecular Weight: 389.36
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2018-03-23 08:00:00
  • Modify Date: 2024-01-06 22:08:11
  • 8-(Phenylmethoxy)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name 8-Benzyloxyguanosine
Synonyms 8-Benzyloxy-guanosin
Description 8-(Phenylmethoxy)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

Density 1.8g/cm3
Boiling Point 772ºC at 760mmHg
Molecular Formula C17H19N5O6
Molecular Weight 389.36
Flash Point 420.7ºC
Exact Mass 389.13400
PSA 168.74000
Index of Refraction 1.796

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3868-36-8 structure

3868-36-8

Literature: Slade, Peter G.; Priestley, Nigel D.; Sugden, Kent D. Organic Letters, 2007 , vol. 9, # 22 p. 4411 - 4414

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3868-36-8 structure

3868-36-8

Literature: Sheu; Foote Journal of the American Chemical Society, 1995 , vol. 117, # 24 p. 6439 - 6442

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3868-36-8 structure

3868-36-8

Literature: Nguyen, Khiem V.; Muller, James G.; Burrows, Cynthia J. Tetrahedron Letters, 2011 , vol. 52, # 17 p. 2176 - 2180