3868-31-3

3868-31-3 structure

Name: 8-hydroxyguanosine
Chemical Name: 8-hydroxyguanosine
CAS Number: 3868-31-3
Molecular Formula: C₁₀H₁₃N₅O₆
Molecular Weight: 299.240
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-08-08 23:46:57
Modify Date: 2025-08-26 00:25:37
8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.

Name	8-hydroxyguanosine
Synonyms	8-Hydroxy Guanosine 8-OXO-G 8-OXOGUANOSINE 8-Oxyguanosin 7,8-dihydro-8-oxo-Guanosine 7,8-Dihydroguanosine, 8-oxo- 7,8-dihydro-8-oxo-guanosin 8-OHG 8-oxo-7,8-dihydro-guanosine 8-OH-GUO 8-Hydroxy-guanosin 8-Oxo-7,8-dihydroguanosine 8-Oxo-D-guanosine 8-Oxoguanosin

Description	8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.
Related Catalog	Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Natural Products >> Others
Target	Human Endogenous Metabolite
References	[1]. Fiala ES, et al. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989 Oct 15;49(20):5518-22. [2]. Abe T, et al. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):447-50.

3868-36-8

~81%

3868-31-3

Literature: Lin; Cheng; Ishiguro; Sartorelli Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1194 - 1198

118-00-3

~0%

3868-31-3

74227-98-8

104826-07-5

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

4016-63-1

3868-31-3

Literature: Lin; Cheng; Ishiguro; Sartorelli Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1194 - 1198

104826-07-5

~66%

3868-31-3

74227-98-8

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

5614-64-2

3868-31-3

Literature: Oklahoma Medical Research Foundation Patent: US4950665 A1, 1990 ;

74227-98-8

3868-31-3

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

104826-07-5

3868-31-3

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

961-07-9

3868-31-3

88847-89-6

Literature: Nishida, Yuzo; Ito, Sayo Journal of the Chemical Society, Chemical Communications, 1995 , # 12 p. 1211 - 1212