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52434-75-0

52434-75-0 structure

52434-75-0 structure

Name: LHRH (1-5) (free acid) trifluoroacetate salt
Chemical Name: lhrh (1-5)
CAS Number: 52434-75-0
Molecular Formula: C₃₄H₃₈N₈O₉
Molecular Weight: 702.71
Catalog: Research Areas Others
Create Date: 2018-12-25 12:24:06
Modify Date: 2026-08-06 12:40:34
LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].

Name	lhrh (1-5)
Synonyms	PGLU-HIS-TRP-SER-TYR 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosine Leuprorelin (Leuprolide) Impurity 13 Goserelin Impurity 41 TFA Salt pglu-his-trp-ser-tyr PYR-HIS-TRP-SER-TYR-OH Goserelin Impurity 26 Acetate pyr-his-trp-ser-tyr-oh LHRH , free acid Leuprorelin (Leuprolide) Impurity Goserelin Impurity 13 L-Tyrosine, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl

Description	LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. McDermott JR, et al. Mechanism of degradation of LH-RH and neurotensin by synaptosomal peptidases. Peptides. 1983 Jan-Feb;4(1):25-30. [2]. Yokosawa H, et al. Degradation of luteinizing hormone-releasing hormone by neuroblastoma cells and their membrane: evidence for the involvement of a thiol protease and angiotensin-converting enzyme. J Neurochem. 1987 Jan;48(1):293-8.

Molecular Formula	C₃₄H₃₈N₈O₉
Molecular Weight	702.71
Exact Mass	702.27600
PSA	267.73000
LogP	0.81160

142822-22-8 structure

142822-22-8

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

16874-12-7 structure

16874-12-7

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

142822-21-7 structure

142822-21-7

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

142822-20-6 structure

142822-20-6

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

25575-88-6 structure

25575-88-6

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

20696-57-5 structure

20696-57-5

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

33217-51-5 structure

33217-51-5

~%

52434-75-0 structure

52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

2130-96-3 structure

2130-96-3

23680-31-1 structure

23680-31-1

13139-14-5 structure

13139-14-5

25024-53-7 structure

25024-53-7

~%

Detail

Literature: Stetler-Stevenson, Mary Alice; Yang, Dai Chang; Lipkowski, Andrew; McCartney, Linda; Peterson, Darryl; Fluoret, George Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 688 - 692

Precursor 9
142822-22-8 16874-12-7 142822-21-7 25575-88-6
20696-57-5 33217-51-5 2130-96-3 23680-31-1
13139-14-5
DownStream 0

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