LHRH (1-5) (free acid) trifluoroacetate salt

Modify Date: 2024-01-02 22:04:52

LHRH (1-5) (free acid) trifluoroacetate salt Structure
LHRH (1-5) (free acid) trifluoroacetate salt structure
Common Name LHRH (1-5) (free acid) trifluoroacetate salt
CAS Number 52434-75-0 Molecular Weight 702.71
Density N/A Boiling Point N/A
Molecular Formula C34H38N8O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LHRH (1-5) (free acid) trifluoroacetate salt


LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].

 Names

Name lhrh (1-5)
Synonym More Synonyms

  Biological Activity

Description LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].
Related Catalog
References

[1]. McDermott JR, et al. Mechanism of degradation of LH-RH and neurotensin by synaptosomal peptidases. Peptides. 1983 Jan-Feb;4(1):25-30.  

[2]. Yokosawa H, et al. Degradation of luteinizing hormone-releasing hormone by neuroblastoma cells and their membrane: evidence for the involvement of a thiol protease and angiotensin-converting enzyme. J Neurochem. 1987 Jan;48(1):293-8.  

 Chemical & Physical Properties

Molecular Formula C34H38N8O9
Molecular Weight 702.71
Exact Mass 702.27600
PSA 267.73000
LogP 0.81160

 Synthetic Route

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

LHRH (1-5) (free acid) trifluoroacetate salt Structure

LHRH (1-5) (fre...

CAS#:52434-75-0

Literature: Slomczynska, Urszula; Leplawy, Tomasz; Leplawy, Miroslaw, T. Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992 , vol. 47, # 10 p. 1424 - 1430

~%

Detail
Literature: Stetler-Stevenson, Mary Alice; Yang, Dai Chang; Lipkowski, Andrew; McCartney, Linda; Peterson, Darryl; Fluoret, George Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 688 - 692

 Synonyms

pglu-his-trp-ser-tyr
pyr-his-trp-ser-tyr-oh