64294-95-7

64294-95-7 structure

Name: Setastine
Chemical Name: 1-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]azepane
CAS Number: 64294-95-7
Molecular Formula: C₂₂H₂₈ClNO
Molecular Weight: 357.91700
Catalog: API Antiallergic Antihistamine
Create Date: 2018-09-17 12:05:11
Modify Date: 2024-01-05 18:20:40
Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research[1]<.

Name	1-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]azepane
Synonyms	1H-Azepine,1-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)hexahydro Setastine Setastine [INN] Setastina Setastinum 1-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)azepane Setastinum [INN-Latin]

Description	Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research[1]<.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	IC50:Histamine Hi-receptor[1]
References	[1]. Németh, A., & Huszti, Z. (1988). The effect of a new antihistamine drug, Loderix® (EGIS-2062), on stimulus-evoked histamine release from rat peritoneal mast cells. Agents and Actions, 23(3-4), 194–197.

HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%