5601-74-1

5601-74-1 structure

Name: Ophiobolin B
Chemical Name: Ophiobolin B
CAS Number: 5601-74-1
Molecular Formula: C₂₅H₃₈O₄
Molecular Weight: 402.56700
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2016-05-24 05:12:59
Modify Date: 2025-08-27 07:56:29
Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement[1]. The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL[2].

Name	Ophiobolin B
Synonyms	3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al Cochliobolin B

Description	Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement[1]. The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Anti-infection >> Fungal
Target	Fungal[2]
References	[1]. Gianani L, et al. Effects of ophiobolin B on cell enlargement and H(+)/K (+) exchange in maize coleoptile tissues. Planta. 1979 Jan;146(3):271-4. [2]. Krizsán K, et al. Effect of the sesterterpene-type metabolites, ophiobolins A and B, on zygomycetes fungi. FEMS Microbiol Lett. 2010 Dec;313(2):135-40.