137863-20-8

137863-20-8 structure

Name: Valsartan benzyl ester
Chemical Name: (S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate
CAS Number: 137863-20-8
Molecular Formula: C₃₁H₃₅N₅O₃
Molecular Weight: 525.641
Create Date: 2018-05-15 08:00:00
Modify Date: 2025-08-25 23:21:51
Valsartan benzyl ester is a Valsartan intermediate.

Name	(S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate
Synonyms	Valsartan benzyl ester L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester Benzyl N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valinate benzyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate T5MNNNJ ER BR D1NV4&YVO1R&Y1&1 &&L or S Form Phenylmethyl N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valinate Benzyl N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-L-valinate Benzyl N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valinate Valsartan Impurity 2

Hazard Codes	Xn

137864-44-9

~90%

137863-20-8

Literature: ENANTIA, S. L. Patent: WO2006/67216 A2, 2006 ; Location in patent: Page/Page column 29 ; WO 2006/067216 A2

137864-22-3

137863-20-8

Literature: WO2005/49588 A1, ; Page/Page column 6 ;

676129-93-4

638-29-9

137863-20-8

Literature: WO2004/26847 A1, ; Page 26; 32-33 ; WO 2004/026847 A1

67-56-1

137864-44-9

~0%

137863-20-8

596-31-6

Literature: ZENTIVA, a.s. Patent: WO2005/21535 A2, 2005 ; Location in patent: Page/Page column 15 ;

1315376-91-0

137863-20-8

Literature: Organic Process Research and Development, , vol. 15, # 5 p. 986 - 988