Name | ritanserin |
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Synonyms |
6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one
Ritanserinum Ritanserina Ritanserine risperidone Tiserton |
Description | Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors[1]. |
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Related Catalog | |
Target |
IC50: 0.9 nM (5-HT2 receptor), 35 nM (H1 receptor), 70 nM (D2 receptor), 97 nM (α1 receptor), 150 nM (α2 receptor)[1] |
In Vitro | Ritanserin (R 55667) is a highly potent, relatively selective, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine-H1 (IC50, 35 nM), Dopamine-D2 (IC50, 70 nM), Adrenergic-α1 (IC50, 97 nM), Adrenergic-α2 receptor (IC50, 150 nM)[1]. |
References |
Density | 1.3g/cm3 |
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Boiling Point | 618.7ºC at 760 mmHg |
Molecular Formula | C27H25F2N3OS |
Molecular Weight | 477.56900 |
Flash Point | 328ºC |
Exact Mass | 477.16900 |
PSA | 65.85000 |
LogP | 5.42090 |
Index of Refraction | 1.646 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
RIDADR | NONH for all modes of transport |