Ritanserin
Ritanserin structure
|
Common Name | Ritanserin | ||
|---|---|---|---|---|
| CAS Number | 87051-43-2 | Molecular Weight | 477.56900 | |
| Density | 1.3g/cm3 | Boiling Point | 618.7ºC at 760 mmHg | |
| Molecular Formula | C27H25F2N3OS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 328ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of RitanserinRitanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors[1]. |
| Name | ritanserin |
|---|---|
| Synonym | More Synonyms |
| Description | Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.9 nM (5-HT2 receptor), 35 nM (H1 receptor), 70 nM (D2 receptor), 97 nM (α1 receptor), 150 nM (α2 receptor)[1] |
| In Vitro | Ritanserin (R 55667) is a highly potent, relatively selective, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine-H1 (IC50, 35 nM), Dopamine-D2 (IC50, 70 nM), Adrenergic-α1 (IC50, 97 nM), Adrenergic-α2 receptor (IC50, 150 nM)[1]. |
| References |
| Density | 1.3g/cm3 |
|---|---|
| Boiling Point | 618.7ºC at 760 mmHg |
| Molecular Formula | C27H25F2N3OS |
| Molecular Weight | 477.56900 |
| Flash Point | 328ºC |
| Exact Mass | 477.16900 |
| PSA | 65.85000 |
| LogP | 5.42090 |
| Index of Refraction | 1.646 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| RIDADR | NONH for all modes of transport |
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