Name | DPPE fumarate |
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Description | MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake[1]. |
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Related Catalog | |
Target |
IC50: 11.63 (MC4) |
In Vitro | MCL0020 inhibited [125I][N1e4, D-Phe7]α-MSH binding to membranes of COS-1 cells with IC50 values of 11.63[1]. |
In Vivo | MCL0020 attenuates swim stress-induced anxiogeniclike behavior in light/dark exploration tests in mice[1]. MCL0020 significantly reverses stress-induced anorexia in rats[1]. |
References |
Molecular Formula | C34H39N7O4 |
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Molecular Weight | 609.71800 |
Exact Mass | 609.30600 |
PSA | 192.29000 |
LogP | 5.06500 |