519148-48-2
519148-48-2 structure
- Name: CJ 033466
- Chemical Name: 5-amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)piperidin-4-yl]methyl]imidazo[1,2-a]pyridine-8-carboxamide
- CAS Number: 519148-48-2
- Molecular Formula: C19H28ClN5O
- Molecular Weight: 377.91200
- Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
- Create Date: 2017-09-06 02:02:51
- Modify Date: 2026-07-16 09:43:02
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CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect[1].
| Name | 5-amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)piperidin-4-yl]methyl]imidazo[1,2-a]pyridine-8-carboxamide |
|---|---|
| Synonyms |
PG-9 maleate
5-Amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl]-imidazo[1,2-a]pyridine-8-cboxamide 5-amino-6-chloro-2-methyl-N-{[1-(2-methylpropyl)piperidin-4-yl]methyl}imidazo[1,2-a]pyridine-8-cboxamide Imidazo[1,2-a]pyridine-8-cboxamide, 5-amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl] UNII-9KUW8W70PJ CJ-033,466 5-HT Rector,Inhibitor,inhibit,gastroprokinetic,CJ-033466,CJ033466,Serotonin Rector,gastrointestinal dysfunction,CJ 033466,5-hydroxytryptamine Rector CJ 033466, 10 mM in DMSO |
| Description | CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect[1]. |
|---|---|
| Related Catalog | |
| Target |
5-HT4 Receptor:9 nM (EC50) |
| References |
| Molecular Formula | C19H28ClN5O |
|---|---|
| Molecular Weight | 377.91200 |
| Exact Mass | 377.19800 |
| PSA | 75.66000 |
| LogP | 3.88610 |
|
~%
519148-48-2 |
| Literature: Uchida, Chikara; Noguchi, Hirohide; Stobie, Alan; Gymer, Geoffrey; Fenwick, David Patent: US2003/92699 A1, 2003 ; |
| Precursor 2 | |
|---|---|
| DownStream 0 | |