CJ 033466

Modify Date: 2025-08-25 13:49:08

CJ 033466 structure	Common Name	CJ 033466
	CAS Number	519148-48-2	Molecular Weight	377.91200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₈ClN₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CJ 033466

CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect[1].

Name	5-amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)piperidin-4-yl]methyl]imidazo[1,2-a]pyridine-8-carboxamide
Synonym	More Synonyms

Description	CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT4 Receptor:9 nM (EC50)
References	[1]. Tadayoshi Mikami, et al. 5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2-alpha]pyridine-8-carboxamide (CJ-033,466), a novel and selective 5-hydroxytryptamine4 receptor partial agonist: pharmacological profile in vitro and gastroprokinetic effect in conscious dogs. J Pharmacol Exp Ther. 2008 Apr;325(1):190-9.

Molecular Formula	C₁₉H₂₈ClN₅O
Molecular Weight	377.91200
Exact Mass	377.19800
PSA	75.66000
LogP	3.88610
InChIKey	ISKHMDNIWXPUGR-UHFFFAOYSA-N
SMILES	Cc1cn2c(N)c(Cl)cc(C(=O)NCC3CCN(CC(C)C)CC3)c2n1

5-amino-6-chlor...

CAS#:519147-88-7

N,N-Carbonyldii...

CAS#:530-62-1

AKOS SB-011

CAS#:258345-24-3

CJ 033466

CAS#:519148-48-2

Literature: Uchida, Chikara; Noguchi, Hirohide; Stobie, Alan; Gymer, Geoffrey; Fenwick, David Patent: US2003/92699 A1, 2003 ;

Precursor 2
CAS#:530-62-1 N,N-Carbonyldii... CAS#:258345-24-3 AKOS SB-011
DownStream 0

Name: NCATS Kinetic Aqueous Solubility Profiling
Source: NCGC
Target: N/A
External Id: ADME-solubility1

Name: Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
Source: NCGC
External Id: IP6K1-p1

Name: Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu...
Source: NCGC
External Id: CYP3A4437

Name: Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2D6395

Name: Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2C9536

Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582

Name: Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu...
Source: NCGC
External Id: CYP3A7681

Name: NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling
Source: NCGC
Target: N/A
External Id: ADME-PAMPA1

Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149

Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150

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UNII-9KUW8W70PJ

CJ-033,466

PG-9 maleate

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CJ 033466
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CJ 033466
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.