68489-09-8

68489-09-8 structure

Name: WS 12
Chemical Name: (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide
CAS Number: 68489-09-8
Molecular Formula: C₁₈H₂₇NO₂
Molecular Weight: 289.41200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
Create Date: 2018-09-29 09:43:32
Modify Date: 2025-08-25 06:56:29
WS-12 is an agonist of TRPM8 with an EC50 of 39 nM.

Name	(1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide
Synonyms	WS 12 7-Hydroxy-DPAT hydrobromide WS-12

Description	WS-12 is an agonist of TRPM8 with an EC50 of 39 nM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Metabolic Disease Research Areas >> Cancer
Target	EC50: 39 nM (TRPM8)[1]
References	[1]. Beck B, et al. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium. 2007 Mar;41(3):285-94.