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2260-08-4

2260-08-4 structure
2260-08-4 structure
  • Name: Acetiromate
  • Chemical Name: 4-(4-acetyloxy-3-iodophenoxy)-3,5-diiodobenzoic acid
  • CAS Number: 2260-08-4
  • Molecular Formula: C15H9I3O5
  • Molecular Weight: 649.94200
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-08-09 11:00:33
  • Modify Date: 2024-02-05 12:25:08
  • Acetiromate is a thyroxine analogue. Acetiromate is an antilipidemic drug for hyperlipidemia[1].

Name 4-(4-acetyloxy-3-iodophenoxy)-3,5-diiodobenzoic acid
Synonyms Adecol
Acetyltriiodothyronine formic acid
TBF 43
Acetiromate
Density 2.351 g/cm3
Boiling Point 561.2ºC at 760 mmHg。 产品描述 安全性:
Molecular Formula C15H9I3O5
Molecular Weight 649.94200
Flash Point 293.2ºC
Exact Mass 649.75800
PSA 72.83000
LogP 4.91620
Vapour Pressure 1.96E-13mmHg at 25°C
Index of Refraction 1.724

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG8597700
CHEMICAL NAME :
Benzoic acid, 3,5-diiodo-4-(4-hydroxy-3-iodophenoxy)-, acetate
CAS REGISTRY NUMBER :
2260-08-4
LAST UPDATED :
198706
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C15-H9-I3-O5
MOLECULAR WEIGHT :
649.94

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 16,431,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
520 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 16,431,1974