1852-49-9
1852-49-9 structure
- Name: Pregnanediol 3-glucuronide
- Chemical Name: Pregnanediol 3α-O-β-D-Glucuronide
- CAS Number: 1852-49-9
- Molecular Formula: C27H44O8
- Molecular Weight: 496.63300
- Catalog: Research Areas Endocrinology
- Create Date: 2018-12-05 20:38:37
- Modify Date: 2026-07-01 10:11:11
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Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species[1].
| Name | Pregnanediol 3α-O-β-D-Glucuronide |
|---|---|
| Synonyms |
5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL GLUCURONIDE
(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[[(3R,5R,8R,9S,10S,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]tetrahydropyran-2-cboxylic acid Pregnanediol-3α-Glucuronoside Pregnanediol 3a-O-β-D-Glucuronide Pregnanediol-3α-Glucuronide PREGNANEDIOL GLUCURONIDE 20α-Hydroxy-5β-pregnan-3α-yl β-D-Glucopyranosiduronic Acid 5β-Pregnane-3α,20α-diol glucuronide Pregnanediol 3α-O-β-D-Glucuronide and Pregnanediol 3α-O-α-D-Glucuronide (90:10 mixture) pregnanediol-3alpha-glucuronide 3alpha,20alpha-dihydroxy-5beta-pregnane 3-glucuronide 3ALPHA,20ALPHA-DIHYDROXY-5BETA-PREGNANE 3-GLUCURONIDE 5-BETA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL 3-GLUCOSIDURONATE 5B-pregnane-3A-20A-diol glucuronide*crystalline 3α,20α-Dihydroxy-5β-pregnane 3-glucuronide Pregnanediol 3-Glucuronide (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[[(3R,5R,8R,9S,10S,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-2-cboxylic acid (3α,5β,20S)-20-Hydroxypregnan-3-yl β-D-Glucopyranosiduronic Acid β-D-Glucopyranosiduronic acid, (3α,5β,20S)-20-hydroxypregnan-3-yl Pregnanediol 3α-monoglucuronide Pregnanediol 3-O-Glucuronide |
| Description | Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species[1]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
| Density | 1.3g/cm3 |
|---|---|
| Boiling Point | 666.4ºC at 760mmHg |
| Melting Point | >94°C (dec.) (lit.) |
| Molecular Formula | C27H44O8 |
| Molecular Weight | 496.63300 |
| Flash Point | 217.2ºC |
| Exact Mass | 496.30400 |
| PSA | 136.68000 |
| LogP | 2.30350 |
| Vapour Pressure | 1.34E-20mmHg at 25°C |
| Index of Refraction | 1.587 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~%
1852-49-9 |
| Literature: Huebner et al. Journal of Biological Chemistry, 1944 , vol. 155, p. 615 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |