Pregnanediol 3-glucuronide

Modify Date: 2024-01-04 15:36:42

Pregnanediol 3-glucuronide Structure
Pregnanediol 3-glucuronide structure
Common Name Pregnanediol 3-glucuronide
CAS Number 1852-49-9 Molecular Weight 496.63300
Density 1.3g/cm3 Boiling Point 666.4ºC at 760mmHg
Molecular Formula C27H44O8 Melting Point >94°C (dec.) (lit.)
MSDS USA Flash Point 217.2ºC

 Use of Pregnanediol 3-glucuronide


Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species[1].

 Names

Name Pregnanediol 3α-O-β-D-Glucuronide
Synonym More Synonyms

 Pregnanediol 3-glucuronide Biological Activity

Description Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Chen J, et al. Quantitation of serum pregnanediol-3-glucuronide level in different endocrine statuses by LC-MS/MS. J Pharm Biomed Anal. 2020;184:113171.

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 666.4ºC at 760mmHg
Melting Point >94°C (dec.) (lit.)
Molecular Formula C27H44O8
Molecular Weight 496.63300
Flash Point 217.2ºC
Exact Mass 496.30400
PSA 136.68000
LogP 2.30350
Vapour Pressure 1.34E-20mmHg at 25°C
Index of Refraction 1.587

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

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Pregnanediol 3-glucuronide Structure

Pregnanediol 3-...

CAS#:1852-49-9

Literature: Huebner et al. Journal of Biological Chemistry, 1944 , vol. 155, p. 615

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles25

More Articles
Progesterone, pregnanediol-3-glucuronide, relaxin and oestrone sulphate concentrations in saliva, milk and urine of female alpacas (Vicugna pacos) and their application in pregnancy diagnosis.

Vet. Rec. 171(8) , 195, (2012)

The pregnancy-associated hormones, progesterone (P4), pregnanediol-3-glucuronide (PdG), relaxin (RLN) and oestrone sulphate (E1S) in plasma, saliva, milk and urine of alpacas were measured in order to...

Factors related to declining luteal function in women during the menopausal transition.

J. Clin. Endocrinol. Metab. 93(5) , 1711-21, (2008)

Reproductive hormones are incompletely characterized during the menopause transition (MT).Increased anovulation and decreased progesterone accompany progress through the MT.The Daily Hormone Study (DH...

Describing ovarian cycles, pregnancy characteristics, and the use of contraception in female white-faced marmosets, Callithrix geoffroyi.

Am. J. Primatol. 74(11) , 1044-53, (2012)

Endocrine data and characteristics of nonconceptive ovarian cycling and pregnancy are limited within the genus Callithrix to the common marmoset (C. jacchus) and Wied's black tufted-ear marmoset (C. k...

 Synonyms

3alpha,20alpha-dihydroxy-5beta-pregnane 3-glucuronide
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