674-81-7

674-81-7 structure
674-81-7 structure

Name 2-nitrosoguanidine
Synonyms 1-Nitrosoguanidine
Nitrosoguanidine
Nitrosoguanidines
Nitrosoguanidin
MFCD00059593
N-Nitrosoguanidine
GUANIDINE,NITROSO
Guanidine, N-nitroso-
Density 1.8±0.1 g/cm3
Boiling Point 131.6±23.0 °C at 760 mmHg
Molecular Formula CH4N4O
Molecular Weight 88.069
Flash Point 33.4±22.6 °C
Exact Mass 88.038513
PSA 91.33000
LogP -1.25
Vapour Pressure 9.2±0.2 mmHg at 25°C
Index of Refraction 1.665

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MF4725000
CHEMICAL NAME :
Guanidine, nitroso-
CAS REGISTRY NUMBER :
674-81-7
LAST UPDATED :
199406
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C-H4-N4-O
MOLECULAR WEIGHT :
88.09
WISWESSER LINE NOTATION :
ONMYZUM

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,563,1993
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,563,1993
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
21 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 23,288,1972
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,563,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83966 No. of Facilities: 61 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 442 (estimated)
Risk Phrases 11-20/21/22-36/37/38
Safety Phrases S16;S26;S36/S37/S39
RIDADR UN 1325

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674-81-7 structure

674-81-7

Literature: Davis; Rosenquist Journal of the American Chemical Society, 1937 , vol. 59, p. 2114 Full Text Show Details Sabetta; Himmelfarb; Smith Journal of the American Chemical Society, 1935 , vol. 57, p. 2478

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674-81-7 structure

674-81-7

Literature: Pellizzari, G. Gazzetta Chimica Italiana, 1921 , vol. 51 I, p. 224 - 228

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674-81-7 structure

674-81-7

Literature: Pellizzari Gazzetta Chimica Italiana, 1921 , vol. 51 I, p. 226 Anm. Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1921 , vol. <5>30 I, p. 173 Anm.

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674-81-7 structure

674-81-7

Literature: Thiele Justus Liebigs Annalen der Chemie, 1892 , vol. 270, p. 44 Justus Liebigs Annalen der Chemie, 1892 , vol. 271, p. 129

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674-81-7 structure

674-81-7

Literature: Pellizzari Gazzetta Chimica Italiana, 1921 , vol. 51 I, p. 226 Anm. Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1921 , vol. <5>30 I, p. 173 Anm.