3052-06-0
3052-06-0 structure
- Name: 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-
- Chemical Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione
- CAS Number: 3052-06-0
- Molecular Formula: C9H11IN2O6
- Molecular Weight: 370.10
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-03-26 05:07:50
- Modify Date: 2025-08-27 13:40:20
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1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione |
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| Synonyms | 5-Iodoarabinouridine |
| Description | 1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.27g/cm3 |
|---|---|
| Molecular Formula | C9H11IN2O6 |
| Molecular Weight | 370.10 |
| Exact Mass | 369.96600 |
| PSA | 124.78000 |
| Index of Refraction | 1.748 |
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~92%
3052-06-0 |
| Literature: Kumar; Wiebe; Knaus Canadian Journal of Chemistry, 1994 , vol. 72, # 9 p. 2005 - 2010 |
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~80%
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| Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568 |
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| Literature: Cech, D.; Schwarz, B.; Pein, C. D. Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 3 p. 387 - 392 |
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3052-06-0 |
| Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568 |
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~%
3052-06-0 |
| Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568 |
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~%
3052-06-0 |
| Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568 |
| Precursor 6 | |
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| DownStream 0 | |