2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-

Modify Date: 2024-01-08 06:06:32

2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo- Structure
2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo- structure
Common Name 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-
CAS Number 3052-06-0 Molecular Weight 370.10
Density 2.27g/cm3 Boiling Point N/A
Molecular Formula C9H11IN2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-


1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione
Synonym More Synonyms

  Biological Activity

Description 1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.27g/cm3
Molecular Formula C9H11IN2O6
Molecular Weight 370.10
Exact Mass 369.96600
PSA 124.78000
Index of Refraction 1.748

 Synonyms

5-Iodoarabinouridine