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1024-99-3

1024-99-3 structure
1024-99-3 structure
  • Name: 5-Iodouridine
  • Chemical Name: 5-Iodouridine
  • CAS Number: 1024-99-3
  • Molecular Formula: C9H11IN2O6
  • Molecular Weight: 370.10
  • Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
  • Create Date: 2018-03-24 08:00:00
  • Modify Date: 2024-01-03 15:12:56
  • 5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 5-Iodouridine
Synonyms 5-Iodouridine
5-Iod-uridin
5-Iodoruidine
2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine
Uridine, 5-iodo-
5-iodo-uridine
EINECS 213-833-1
5-Jod-uridin
5-Iodo-D-uridine
MFCD00006532
Description 5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 2.3±0.1 g/cm3
Melting Point 205-207ºC (dec.)(lit.)
Molecular Formula C9H11IN2O6
Molecular Weight 370.10
Exact Mass 369.966156
PSA 124.78000
LogP -0.43
Index of Refraction 1.748
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 22-24/25-36/37/39-27-26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934999090

~92%

1024-99-3 structure

1024-99-3

Literature: Kumar; Wiebe; Knaus Canadian Journal of Chemistry, 1994 , vol. 72, # 9 p. 2005 - 2010

~94%

1024-99-3 structure

1024-99-3

Literature: Asakura, Jun-ichi; Robins, Morris J. Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4928 - 4933

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1024-99-3 structure

1024-99-3

Literature: Journal of Organic Chemistry, , vol. 55, # 16 p. 4928 - 4933

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1024-99-3 structure

1024-99-3

Literature: Angewandte Chemie - International Edition, , vol. 50, # 9 p. 2155 - 2158
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%