911-40-0
911-40-0 structure
- Name: 7-Keto-3α,12-α-dihydroxycholanic Acid
- Chemical Name: 3α,12α-dihydroxy-7-oxo-5β-cholanic acid
- CAS Number: 911-40-0
- Molecular Formula: C24H38O5
- Molecular Weight: 406.55600
- Catalog: Research Areas Others
- Create Date: 2018-12-26 16:09:50
- Modify Date: 2026-07-02 06:22:58
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7-keto-lithocholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-lithocholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition[1][2].
| Name | 3α,12α-dihydroxy-7-oxo-5β-cholanic acid |
|---|---|
| Synonyms |
Deoxycholic Acid 7-Oxo Impurity
Cholan-24-oic acid,3,12-dihydroxy-7-oxo-, (3a,5b,12a) 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL-7-ONE 7-Ketodeoxycholic acid 7-Oxodeoxycholic acid 7-DEHYDROCHOLIC ACID 7-Oxodeoxycholic Acid Cholan-24-oic acid, 3,12-dihydroxy-7-oxo-, (3α,5β,12α) 7-ketodeoxycholate 5β-Cholanic Acid-3α,12α-diol-7-one 5β-CHOLANIC acid-3α, 12α-DIOL-7-ONE Cholic Acid Impurity 15 (7-Ketodeoxycholic Acid) Ursodeoxycholic Acid Impurity 11 3a,12a-dihydroxy-7-oxo-5b-cholan-24-oic acid 7-oxodeoxycholate 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholan-24-oic Acid 3alpha,12alpha-Diol-7-one-5beta-cholanoic acid 3,12-DIHYDROXY-7-OXOCHOLAN-24-OIC ACID 7-KETODEOXYCHOLIC ACID (4R)-4-((3R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (3alpha,5beta,12alpha)-3,12-Dihydroxy-7-oxocholan-24-oic acid 7-Ketodeoxycholic acida 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid 7-keto-deoxycholic acid, 10 mM in DMSO Cholic Acid Impurity 12 (7-Ketodeoxycholic Acid) (4R)-4-[(3R,5S,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid 3α,12α-dihydroxy-7-keto-5β-cholan-24-oic acid 3α,12α-Dihydroxy-7-keto-5β-cholanic Acid 7-Keto-3alpha,12alpha-dihydroxycholanic acid (3α,5β,12α)-3,12-Dihydroxy-7-oxo-cholan-24-oic Acid (R)-4-((3R,5S,8R,9S,10S,12S,13R,14S,17R)-3,12-Dihydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
| Description | 7-keto-lithocholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-lithocholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | 7-keto-lithocholic acid shows an increasing bioconversion rate with addition of an equimolar concentration of deoxycholic acid (which itself is not metabolized)[1]. 7-keto-lithocholic acid is induced by deoxycholic acid and then it's metabolized[1]. E. lentum-like c-25 converts 81.7% of 2 mM cholic acid to deoxycholic acid and 3.7% to 7-keto-deoxycholic acid under anaerobic incubation[2]. E. lentum-like c-25 converts 91.5% of 150 mg/mL cholic acid to deoxycholic acid and 1.1% to 7-keto-deoxycholic acid under anaerobic incubation[2]. |
| References |
| Density | 1.18g/cm3 |
|---|---|
| Boiling Point | 583ºC at 760mmHg |
| Melting Point | 54-60ºC |
| Molecular Formula | C24H38O5 |
| Molecular Weight | 406.55600 |
| Flash Point | 320.4ºC |
| Exact Mass | 406.27200 |
| PSA | 94.83000 |
| LogP | 3.65690 |
| Index of Refraction | 1.55 |
| Hazard Codes | T |
|---|
| Precursor 0 | |
|---|---|
| DownStream 3 | |
