2955-27-3

2955-27-3 structure

Name: Ursocholic acid
Chemical Name: Ursocholic Acid
CAS Number: 2955-27-3
Molecular Formula: C₂₄H₄₀O₅
Molecular Weight: 408.57100
Catalog: Natural Products Others
Create Date: 2017-10-25 22:54:22
Modify Date: 2024-01-09 12:08:55
Ursocholic acid, a bile acid found predominantly in bile of mammals, is an inhibitor of 7α-hydroxysteroid dehydrogenase and hepatocyte nuclear factor 1α.

Name	Ursocholic Acid
Synonyms	3-Epicholic acid 3\|A-Cholic Acid 3\|A,7\|A,12\|A-Trihydroxy-5\|A-cholanoic Acid

Description	Ursocholic acid, a bile acid found predominantly in bile of mammals, is an inhibitor of 7α-hydroxysteroid dehydrogenase and hepatocyte nuclear factor 1α.
Related Catalog	Natural Products >> Others Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. MacDonald IA, et al. Formation of ursodeoxycholic acid from chenodeoxycholic acid by a 7 beta-hydroxysteroid dehydrogenase-elaborating Eubacterium aerofaciens strain cocultured with 7 alpha-hydroxysteroid dehydrogenase-elaborating organisms. Appl Environ Microbiol. 1982 Nov;44(5):1187-95. [2]. Lee HI, et al. Ursodeoxycholic acid, an inhibitor of hepatocyte nuclear factor 1α, did not increase the systemic exposure of pitavastatin. Int J Clin Pharmacol Ther. 2014 Nov;52(11):981-5.