5633-14-7

5633-14-7 structure
5633-14-7 structure
  • Name: Benzetimide hydrochloride
  • Chemical Name: 3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride
  • CAS Number: 5633-14-7
  • Molecular Formula: C23H27ClN2O2
  • Molecular Weight: 398.926
  • Catalog: Signaling Pathways GPCR/G Protein mAChR
  • Create Date: 2018-10-01 10:21:14
  • Modify Date: 2024-01-04 00:02:15
  • Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist. Target: mAChR

Name 3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride
Synonyms Dioxatrine
1'-Benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione hydrochloride (1:1)
Spasmentral
R 4929
Benzetimide HCl
EINECS 227-072-8
[3,4'-Bipiperidine]-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, hydrochloride (1:1)
McN-JR4929
BENZETIMIDE HYDROCHLORIDE
Benzetimide (hydrochloride)
Description Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist. Target: mAChR
Related Catalog
Boiling Point 543.9ºC at 760 mmHg
Molecular Formula C23H27ClN2O2
Molecular Weight 398.926
Flash Point 282.7ºC
Exact Mass 398.176117
PSA 52.90000
LogP 4.28900
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA4030000
CHEMICAL NAME :
Glutarimide, 2-(1-benzyl-4-piperidyl)-2-phenyl-, hydrochloride
CAS REGISTRY NUMBER :
5633-14-7
LAST UPDATED :
199707
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C23-H26-N2-O2.Cl-H
MOLECULAR WEIGHT :
398.97
WISWESSER LINE NOTATION :
T6VMVTJ DR& D- DT6NTJ A1R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
37600 ug/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1365,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
680 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,283,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
46 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1365,1971
Hazard Codes Xn
Risk Phrases 22
RIDADR UN 3249
Packaging Group III
Hazard Class 6.1(b)
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