267243-64-1

267243-64-1 structure

Name: N-(3-CHLORO-4-FLUOROPHENYL)-7-(3-MORPHOLINOPROPOXY)-6-NITROQUINAZOLIN-4-AMINE
Chemical Name: N-(3-chloro-4-fluorophenyl)-7-(3-morpholin-4-ylpropoxy)-6-nitroquinazolin-4-amine
CAS Number: 267243-64-1
Molecular Formula: C₂₁H₂₁ClFN₅O₄
Molecular Weight: 461.87400
Create Date: 2018-12-31 20:35:48
Modify Date: 2024-01-16 11:14:00

Name	N-(3-chloro-4-fluorophenyl)-7-(3-morpholin-4-ylpropoxy)-6-nitroquinazolin-4-amine
Synonyms	(3-chloro-4-fluorophenyl)-[7-(3-morpholino-4-yl-propoxy)-6-nitroquinazolin-4-yl]-amine (3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitro-quinazoline-4-yl]-amine I14-9229 (3-CHLORO-4-FLOUROPHENYL)-[7-(3-MORPHOLIN-4-YL-PROPOXY)-6-NITRO-QUINAZOLINE-4YL]-AMINE N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine 4-[N-(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-nitroquinazoline (3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitroquinazolin-4-yl]-amine

Density	1.418g/cm3
Boiling Point	637.065ºC at 760 mmHg
Molecular Formula	C₂₁H₂₁ClFN₅O₄
Molecular Weight	461.87400
Flash Point	339.085ºC
Exact Mass	461.12700
PSA	105.33000
LogP	4.70930
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.649

267243-68-5

267243-64-1

Literature: Warner-Lambert Company LLC Patent: US6664390 B2, 2003 ; Location in patent: Page column 8 ;

4441-30-9

367-21-5

162012-69-3

~94%

267243-64-1

Literature: Barth, Hubert; Bridges, Alexander James; Heemstra, Ronald J.; Horne, Nicole Marcia; Hughes, Robert Craig; Jacks, Thomas Elliott; McNamara, Dennis Joseph; Schneider, Simon; Steiner, Klaus; Toogood, Peter Laurence; Winters, Roy Thomas Patent: US2004/158065 A1, 2004 ; Location in patent: Page 20 ;

4441-30-9

162012-67-1

~65%

267243-64-1

Literature: Hur, Wooyoung; Velentza, Anastasia; Kim, Sungjoon; Flatauer, Laura; Jiang, Xinnong; Valente, David; Mason, Daniel E.; Suzuki, Melissa; Larson, Brad; Zhang, Jianming; Zagorska, Anna; DiDonato, Michael; Nagle, Advait; Warmuth, Markus; Balk, Steven P.; Peters, Eric C.; Gray, Nathanael S. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 22 p. 5916 - 5919

4441-30-9

367-21-5

865-47-4

162012-69-3

Detail

Literature: Barth, Hubert; Steiner, Klaus; Schneider, Simon Patent: US2003/158408 A1, 2003 ;

367-21-5

267243-64-1

Literature: Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

162012-70-6

267243-64-1

Precursor 7
267243-68-5 4441-30-9 367-21-5 162012-69-3
162012-67-1 865-47-4 162012-70-6
DownStream 1
267243-68-5

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