928-81-4
928-81-4 structure
- Name: 6-Oxohexanoic acid
- Chemical Name: 6-oxohexanoic acid
- CAS Number: 928-81-4
- Molecular Formula: C6H10O3
- Molecular Weight: 130.14200
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2017-05-30 11:56:32
- Modify Date: 2024-01-09 18:53:12
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6-Oxohexanoic acid is a non-cleavable modified MMAF-C5-COOH linker and can be used in the synthesis of modified MMAF-C5-COOH, a drug-linker conjugate for ADC[1].
| Name | 6-oxohexanoic acid |
|---|---|
| Synonyms |
Hexan-1-one-6-carboxylate
6-Oxohexanoate 6-OXO-HEXANOIC ACID adipic semialdehyde 6-Oxohexanoic acid monoaldehyde of adipic acid 6-oxo-n-hexanoic acid 1-hexanal-6-carboxylic acid adipic acid monoaldehyde 5-carbohydroxy-1-pentanal 5-formylvaleric acid Hexanoic acid,6-oxo adipic monoaldehyde |
| Description | 6-Oxohexanoic acid is a non-cleavable modified MMAF-C5-COOH linker and can be used in the synthesis of modified MMAF-C5-COOH, a drug-linker conjugate for ADC[1]. |
|---|---|
| Related Catalog | |
| In Vitro | MMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC50s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay[2]. |
| References |
| Density | 1.088g/cm3 |
|---|---|
| Boiling Point | 263.7ºC at 760mmHg |
| Molecular Formula | C6H10O3 |
| Molecular Weight | 130.14200 |
| Flash Point | 127.5ºC |
| Exact Mass | 130.06300 |
| PSA | 54.37000 |
| LogP | 0.83030 |
| Index of Refraction | 1.441 |
| HS Code | 2918300090 |
|---|
| Precursor 10 | |
|---|---|
| DownStream 8 | |
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |