114531-28-1

114531-28-1 structure

Name: Spiramine A
Chemical Name: Spiramine A
CAS Number: 114531-28-1
Molecular Formula: C₂₄H₃₃NO₄
Molecular Weight: 399.523
Catalog: Natural product Alkaloid
Create Date: 2016-07-13 19:10:04
Modify Date: 2024-03-09 13:37:49
Spiramine A (Spiramine C acetate (ester)) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC50 vallue of 6.7 μM[1].

Name	Spiramine A
Synonyms	(1R,2R,3S,5S,7R,8R,12R,13S,18R,21R)-12-Methyl-4-methylene-14,19-dioxa-17-azaheptacyclo[10.7.2.2.0.0.0.0]tricos-3-yl acetate spiramine B (1R,2R,3S,5S,7R,8R,12R,13R,18R,21R)-12-Methyl-4-methylene-14,19-dioxa-17-azaheptacyclo[10.7.2.2.0.0.0.0]tricos-3-yl acetate

Description	Spiramine A (Spiramine C acetate (ester)) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC50 vallue of 6.7 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Li L, et al. Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica. Eur J Pharmacol. 2002 Aug 2;449(1-2):23-8.

Hazard Codes	Xi