126716-36-7
126716-36-7 structure
- Name: Gancaonin I
- Chemical Name: gancaonin I
- CAS Number: 126716-36-7
- Molecular Formula: C21H22O5
- Molecular Weight: 354.396
- Catalog: Natural product Phenols
- Create Date: 2017-04-12 14:40:56
- Modify Date: 2024-01-12 23:16:15
-
Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis[1].
| Name | gancaonin I |
|---|---|
| Synonyms |
4-[4,6-Dimethoxy-5-(3-methyl-2-buten-1-yl)-1-benzofuran-2-yl]-1,3-benzenediol
4-[4,6-dimethoxy-5-(3-methylbut-2-en-1-yl)-1-benzofuran-2-yl]benzene-1,3-diol 1,3-Benzenediol, 4-[4,6-dimethoxy-5-(3-methyl-2-buten-1-yl)-2-benzofuranyl]- 4-[4,6-Dimethoxy-5-(3-methyl-but-2-enyl)-benzofuran-2-yl]-benzene-1,3-diol Gancaonin I 4-(4,6-Dimethoxy-5-(3-methyl-but-2-enyl)-benzofuran-2-yl)-benzene-1,3-diol 4-[4,6-dimethoxy-5-(3-methylbut-2-enyl)-1-benzofuran-2-yl]benzene-1,3-diol |
| Description | Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 534.2±45.0 °C at 760 mmHg |
| Molecular Formula | C21H22O5 |
| Molecular Weight | 354.396 |
| Flash Point | 276.9±28.7 °C |
| Exact Mass | 354.146729 |
| PSA | 72.06000 |
| LogP | 4.45 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.611 |
| Hazard Codes | Xi |
|---|
|
~%
126716-36-7 |
| Literature: Kiuchi, Fumiyuki; Chen, Xing; Tsuda, Yoshisuke Heterocycles, 1990 , vol. 31, # 4 p. 629 - 636 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |