181701-06-4

181701-06-4 structure
181701-06-4 structure
  • Name: InteriotherinA
  • Chemical Name: interiotherin A
  • CAS Number: 181701-06-4
  • Molecular Formula: C29H28O8
  • Molecular Weight: 504.52800
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2017-10-16 10:01:56
  • Modify Date: 2024-01-11 10:06:05
  • Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].

Name interiotherin A
Synonyms Interiotherin A
Description Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].
Related Catalog
In Vitro Interiotherin A (Compounds 1) (0.8-100µg/mL; 4 hours) inhibits HIV replication with EC50 values of 3.1 µg/mL[1]. Cell Cytotoxicity Assay[1] Cell Line: T cell line: HS1 Concentration: 100 µg/mL, 20 µg/mL, 4 µg/mL, and 0.8 µg/mL Incubation Time: 4 hours Result: Exhibited anti-HIV activity.
References

[1]. Chen DF, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8.

Density 1.36g/cm3
Boiling Point 643.3ºC at 760 mmHg
Melting Point 153-154 °C
Molecular Formula C29H28O8
Molecular Weight 504.52800
Flash Point 273.8ºC
Exact Mass 504.17800
PSA 81.68000
LogP 5.55460
Vapour Pressure 1.93E-16mmHg at 25°C
Index of Refraction 1.64