InteriotherinA

Modify Date: 2024-01-11 10:06:05

InteriotherinA Structure
InteriotherinA structure
Common Name InteriotherinA
CAS Number 181701-06-4 Molecular Weight 504.52800
Density 1.36g/cm3 Boiling Point 643.3ºC at 760 mmHg
Molecular Formula C29H28O8 Melting Point 153-154 °C
MSDS N/A Flash Point 273.8ºC

 Use of InteriotherinA


Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].

 Names

Name interiotherin A
Synonym More Synonyms

 InteriotherinA Biological Activity

Description Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].
Related Catalog
In Vitro Interiotherin A (Compounds 1) (0.8-100µg/mL; 4 hours) inhibits HIV replication with EC50 values of 3.1 µg/mL[1]. Cell Cytotoxicity Assay[1] Cell Line: T cell line: HS1 Concentration: 100 µg/mL, 20 µg/mL, 4 µg/mL, and 0.8 µg/mL Incubation Time: 4 hours Result: Exhibited anti-HIV activity.
References

[1]. Chen DF, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8.

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 643.3ºC at 760 mmHg
Melting Point 153-154 °C
Molecular Formula C29H28O8
Molecular Weight 504.52800
Flash Point 273.8ºC
Exact Mass 504.17800
PSA 81.68000
LogP 5.55460
Vapour Pressure 1.93E-16mmHg at 25°C
Index of Refraction 1.64

 Synonyms

Interiotherin A
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