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85532-77-0

85532-77-0 structure
85532-77-0 structure
  • Name: Safflor yellow A
  • Chemical Name: safflor yellow (A)
  • CAS Number: 85532-77-0
  • Molecular Formula: C27H30O15
  • Molecular Weight: 610.51700
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-05-29 08:00:00
  • Modify Date: 2024-01-06 16:58:44
  • Safflor yellow A, a flavonoid extracted from Carthamus tinctorius L, is a water-soluble monomer of safflor yellow. Safflor yellow A protects rat cardiomyocytes against anoxia/reoxygenation (A/R) injury via inhibiting cellular oxidative stress and apoptosis[1].
Name safflor yellow (A)
Description Safflor yellow A, a flavonoid extracted from Carthamus tinctorius L, is a water-soluble monomer of safflor yellow. Safflor yellow A protects rat cardiomyocytes against anoxia/reoxygenation (A/R) injury via inhibiting cellular oxidative stress and apoptosis[1].
Related Catalog
In Vivo Pretreatment with Safflor yellow A (40, 60 and 80 nM) concentration-dependently blockes the A/R-induced changes in the cardiomyocytes in 1- to 3-d-old Sprague-Dawley rats [1].
References

[1]. Duan JL, et al. Safflor yellow A protects neonatal rat cardiomyocytes against anoxia/reoxygenation injury in vitro. Acta Pharmacol Sin. 2013 Apr;34(4):487-95.
Density 1.81g/cm3
Boiling Point 942.3ºC at 760 mmHg
Molecular Formula C27H30O15
Molecular Weight 610.51700
Flash Point 313ºC
Exact Mass 610.15300
PSA 273.36000
Index of Refraction 1.764

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ0333750
CHEMICAL NAME :
9H-Pyrano(3,2-b)benzofuran-9-one, 2,3,4,4a,6,9b-hexahydro-6-beta-D-glucopyranosyl-2- (hydroxymethyl)-8-(3-(4-hydroxyphenyl)-1-oxo-2-propen yl)-3,4,6,7-tetrahydr oxy-
CAS REGISTRY NUMBER :
85532-77-0
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C27-H30-O15
MOLECULAR WEIGHT :
594.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5530 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 15,348,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5490 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 15,348,1984

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title: CAS No. 85532-77-0 | Chemsrc address: https://m.chemsrc.com/en/baike/783298.html

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