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13655-52-2

13655-52-2 structure
13655-52-2 structure
  • Name: Alprenolol
  • Chemical Name: alprenolol
  • CAS Number: 13655-52-2
  • Molecular Formula: C15H23NO2
  • Molecular Weight: 249.34900
  • Catalog: API Circulatory system medication Antiarrhythmic drug
  • Create Date: 2018-07-21 23:06:12
  • Modify Date: 2025-08-20 12:46:24
  • Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist.The reference for administration is 10 mg/kg.

Name alprenolol
Synonyms Alpheprol
Alprenolol
ALLPRENOLOL
Density 1.007g/cm3
Boiling Point 383.4ºC at 760mmHg
Melting Point 57.5°C
Molecular Formula C15H23NO2
Molecular Weight 249.34900
Flash Point 185.7ºC
Exact Mass 249.17300
PSA 41.49000
LogP 2.54370
Vapour Pressure 1.46E-06mmHg at 25°C
Index of Refraction 1.5250 (estimate)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA5350000
CHEMICAL NAME :
2-Propanol, 1-(o-allylphenoxy)-3-(isopropylamino)-
CAS REGISTRY NUMBER :
13655-52-2
LAST UPDATED :
199606
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C15-H23-N-O2
MOLECULAR WEIGHT :
249.39
WISWESSER LINE NOTATION :
1Y1&M1YQ1OR B2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
210 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UGLAAD Ugeskrift for Laeger. Doctor's Weekly. (Almindelige Danske Laegeforening, Esplanaden 8C4, 1045 Copenhagen K, Denmark) V.1- 1839- Volume(issue)/page/year: 139,2817,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 18,151,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - sympathomimetic
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,1022,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
184 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,137,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
102 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,137,1974
Hazard Codes T: Toxic;
Risk Phrases R23/24/25
Safety Phrases 36/37/39-45
RIDADR UN 3249
Packaging Group III
Hazard Class 6.1(b)
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