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69942-12-7

69942-12-7 structure
69942-12-7 structure
  • Name: N-Boc-DL-serine methyl ester
  • Chemical Name: Methyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate
  • CAS Number: 69942-12-7
  • Molecular Formula: C9H17NO5
  • Molecular Weight: 219.235
  • Catalog: Biochemical Amino acids and their derivatives Serine derivative
  • Create Date: 2018-05-26 08:00:00
  • Modify Date: 2025-08-24 20:55:40
  • N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].

Name Methyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate
Synonyms Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
Methyl N-(tert-butoxycarbonyl)serinate
Methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}serinate
methyl 3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
N-Boc-DL-serine methyl ester
Description N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].
Related Catalog
References

[1]. Yang Yongqing, et al. Method for synthesizing α,β-dehydro-α-amino acid. Patent CN105037210.

[2]. Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476.

[3]. Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.

Density 1.1±0.1 g/cm3
Boiling Point 354.3±32.0 °C at 760 mmHg
Molecular Formula C9H17NO5
Molecular Weight 219.235
Flash Point 168.1±25.1 °C
Exact Mass 219.110672
PSA 88.35000
LogP 0.80
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.461
Storage condition 2-8°C
Hazard Codes Xi
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