17105-15-6

17105-15-6 structure

Name: H-Glu(H-Lys-OH)-OH
Chemical Name: γ-Glu-ε-Lys
CAS Number: 17105-15-6
Molecular Formula: C₁₁H₂₁N₃O₅
Molecular Weight: 275.30200
Catalog: Research Areas Metabolic Disease
Create Date: 2016-01-10 14:50:30
Modify Date: 2024-01-11 17:51:05
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].

Name	γ-Glu-ε-Lys
Synonyms	6-amino-2-[(4-amino-4-carboxybutanoyl)amino]hexanoic acid H-Glu(H-Lys-OH)-OH epsilon-(gamma-Glutamyl)-lysine

Description	Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Siegfried G Priglinger, et al. Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3835-45. [2]. A M El Nahas, et al. Elevated Epsilon-(Gamma-Glutamyl)lysine in Human Diabetic Nephropathy Results From Increased Expression and Cellular Release of Tissue Transglutaminase.Nephron Clin Pract. 2004;97(3):c108-17.

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RIDADR	NONH for all modes of transport

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