113276-94-1
113276-94-1 structure
- Name: h-8 dihydrochloride
- Chemical Name: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide hydrochloride
- CAS Number: 113276-94-1
- Molecular Formula: C12H17Cl2N3O2S
- Molecular Weight: 338.25300
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
- Create Date: 2018-08-19 14:48:14
- Modify Date: 2026-07-01 18:21:53
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H-8 (dihydrochloride) is a cell-permeable, reversible and ATP-competitive PKA inhibitor[1].
| Name | N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide hydrochloride |
|---|---|
| Synonyms |
H-8 HYDROCHLORIDE
H-8 DIHYDROCHLORIDE N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE-5-SULFONAMIDE DIHYDROCHLORIDE 5-IsoquinolinesulfonaMide,N-[2-(MethylaMino)ethyl]-, hydrochloride (1:2) N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE 2HCL H-8 DIHYDROCHLORIDE POTENT INHIBITOR OF C H8 (hydrochloride), (hydrochloride) H8, dihydrochloride salt MFCD00036962 N-(2-[METHYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE H-8 2-(5-isoquinolinylsulfonylamino)ethyl-methylammonium N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE, DI-HCL SALT H-8 dihydrochloride (HPLC) N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE DIHYDROCHLORIDE H-8 dihydrochloride N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide |
| Description | H-8 (dihydrochloride) is a cell-permeable, reversible and ATP-competitive PKA inhibitor[1]. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 473.9ºC at 760 mmHg |
|---|---|
| Melting Point | 221-222℃ (methanol water ) |
| Molecular Formula | C12H17Cl2N3O2S |
| Molecular Weight | 338.25300 |
| Flash Point | 240.4ºC |
| Exact Mass | 337.04200 |
| PSA | 79.47000 |
| LogP | 4.19910 |
| Vapour Pressure | 3.79E-09mmHg at 25°C |
| Storage condition | 2-8°C |
| Water Solubility | ethanol: 25 mg/mL, clear, colorless |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2935009090 |
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113276-94-1 |
| Literature: Journal of Medicinal Chemistry, , vol. 32, # 1 p. 42 - 46 |
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113276-94-1 |
| Literature: Journal of Medicinal Chemistry, , vol. 32, # 1 p. 42 - 46 |
|
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113276-94-1 |
| Literature: Journal of Medicinal Chemistry, , vol. 32, # 1 p. 42 - 46 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |