94529-97-2

94529-97-2 structure

Name: 20-Deoxocarnosol
Chemical Name: (4aR,9S,10aS)-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-9,4a-(epoxymethano)phenanthrene-5,6-diol
CAS Number: 94529-97-2
Molecular Formula: C₂₀H₂₈O₃
Molecular Weight: 316.435
Catalog: Natural product Moss
Create Date: 2017-02-15 23:27:03
Modify Date: 2024-01-09 21:32:13
20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells[1].

Name	(4aR,9S,10aS)-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-9,4a-(epoxymethano)phenanthrene-5,6-diol
Synonyms	(7β)-7,20-Epoxyabieta-8,11,13-triene-11,12-diol 2H-9,4a-(Epoxymethano)phenanthrene-5,6-diol, 1,3,4,9,10,10a-hexahydro-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)- 20-Deoxocarnosol

Description	20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Deoxocarnosol (compound 7) (0-40 µM) shows cytotoxicity with IC50 values of ˃40, 32.70, 15.15, ˃40, 24.79, ˃40 µM for :A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells, respectively[1]. Cell Viability Assay[1] Cell Line: A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells Concentration: 0-40 µM Incubation Time: Result: Showed cytotoxicity with IC50 values of ˃40, 32.70, 15.15, ˃40, 24.79, ˃40 µM for :A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells, respectively.
References	[1]. Guijuan Zheng, et al. Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3H-spiro[benzofuran-2,1′-cyclohexane] motif from Salvia deserta. Org. Chem. Front., 2020,7, 3137-3145.

Hazard Codes	Xi