94529-97-2
94529-97-2 structure
- Name: 20-Deoxocarnosol
- Chemical Name: (4aR,9S,10aS)-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-9,4a-(epoxymethano)phenanthrene-5,6-diol
- CAS Number: 94529-97-2
- Molecular Formula: C20H28O3
- Molecular Weight: 316.435
- Catalog: Natural product Moss
- Create Date: 2017-02-15 23:27:03
- Modify Date: 2024-01-09 21:32:13
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20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells[1].
| Name | (4aR,9S,10aS)-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-9,4a-(epoxymethano)phenanthrene-5,6-diol |
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| Synonyms |
(7β)-7,20-Epoxyabieta-8,11,13-triene-11,12-diol
2H-9,4a-(Epoxymethano)phenanthrene-5,6-diol, 1,3,4,9,10,10a-hexahydro-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)- 20-Deoxocarnosol |
| Description | 20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells[1]. |
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| Related Catalog | |
| In Vitro | Deoxocarnosol (compound 7) (0-40 µM) shows cytotoxicity with IC50 values of ˃40, 32.70, 15.15, ˃40, 24.79, ˃40 µM for :A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells, respectively[1]. Cell Viability Assay[1] Cell Line: A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells Concentration: 0-40 µM Incubation Time: Result: Showed cytotoxicity with IC50 values of ˃40, 32.70, 15.15, ˃40, 24.79, ˃40 µM for :A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells, respectively. |
| References |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 463.1±45.0 °C at 760 mmHg |
| Melting Point | 180-183 ºC |
| Molecular Formula | C20H28O3 |
| Molecular Weight | 316.435 |
| Flash Point | 233.9±28.7 °C |
| Exact Mass | 316.203857 |
| PSA | 49.69000 |
| LogP | 5.03 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.597 |
| Water Solubility | Practically insoluble (0.035 g/L) (25 ºC) |
| Hazard Codes | Xi |
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